Well, maybe not. But probably.
Some things I gathered.
"in the air processors"
I don't think the alliance drugged a planet of 30 million people. I think the alliance put the drug in the air while Miranda was still being terraformed (the scene at the beginning with the giant device spewing clouds while the teacher talks about terraforming... I'm betting that's an air procesor), and it slowly worked its way into the new settlers as time passed.
"They never lie down"
The PAX had a definite affect on more than just aggressive tendencies, it removed any motivation of people to do anything. The folks who had the "normal" reaction eventually just all laid down and stopped doing things.
The reavers had their aggressive tendencies increased, but I think the pax also removed their capability to stop. I think they can't sleep, they've got to be active, they've got to be doing something. They've got no interest in dead people; dead people have stopped, and they don't understand stopped. This would also explain why they constantly mutilate themselves and why they modify their ships so ridiculously. They just can't stop.
"No, I don't."
Book was an operative before he was a Shepherd. Pretty clear.
"I am a leaf on the wind. Watch how I soar."
Wash had to die. He had to die for the plot so Zoe would lose her cool, but more importantly he had to die for philosophical reasons. The dialog is just loaded with wind metaphors. This is the story of Mal's and River's transformations from victims carried along by the tide of the past into masters of their own destiny. In the end, River and Mal both reject the wind, and when the wind dies, the leaf falls to the ground.
"She always loved to dance."
River is the avatar of Shiva, dancing for the destruction and rebirth of the world. If the reavers could ever slow down, she would be a god to them. They're too fried to notice anything, though. The Alliance? The Alliance has no idea what it created.
"Storm's getting worse"
Yep, it is, and there's room for a sequel.
...and a design comment or two.
There's a lot more detail in the sets and CGI, and the reavers' swarm was brilliant. Costumes also show more detail and attention than they did in Firefly.
I'm not sure why, but we didn't see any of the "flying skyscraper" style alliance ships this time around. Every other design under the sun, but nothing resembling the Crimson Permanent Assurance.
How did the alliance preserve Frank Gehry? Alliance cities (particularly the cityscape in the beginning) have a very Gehry look to them, with flowing curvy shapes clad in metal sheeting...
...except for Miranda. I didn't really notice until the overhead shot of the crew walking down the "alley." It looks like it could have been designed by Walter Reimann. Who is Walter Reimann? He's the guy who did the production design in The Cabinet of Dr. Caligari. Miranda has the jarring design of Holstenwall, where acute angles give the impression that something is always closing in on you.